New Orleans, LA |
| 1. | Head southwest on St Charles Ave toward Canal St | 0.7 mi | |
| 2. | At Lee Circle, take the 2nd exit and stay on St Charles Ave | 0.1 mi | |
| 3. | Turn right at Calliope St | 0.2 mi | |
| 4. | Take the I-10 ramp on the left | 0.2 mi | |
| 5. | Merge onto US-90 N | 1.6 mi | |
| 6. | Continue on I-10 W | 23.5 mi | |
| 7. | Take exit 210 to merge onto I-55 N toward Hammond Entering Mississippi | 157 mi | |
| 8. | Take exit 92C to merge onto I-20 E/ Continue to follow I-55 N Entering Tennessee | 205 mi | |
| 9. | Continue on I-240 N (signs for Little Rock/ | 5.1 mi | |
| 10. | Take exit 31B toward Little Rock/ | 0.8 mi | |
| 11. | Merge onto I-40 W Entering Arkansas | 9.3 mi | |
| 12. | Continue on I-55 N (signs for Blytheville/ Entering Missouri | 241 mi | |
| 13. | Take exit 175 to merge onto MO-21A/ | 0.6 mi | |
| 14. | Turn right at Collins Dr | 0.4 mi | |
| 15. | Slight right at W Main St | 0.3 mi |
Festus, MO |



