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100 km
50 mi
Pittsburgh, PA |
| 1. | Head southwest on Grant St toward Oliver Ave | 0.3 mi | |
| 2. | Turn right toward Grant St | 33 ft | |
| 3. | Turn left at Grant St | 39 ft | |
| 4. | Turn right to merge onto I-376 E toward Monroeville | 13.9 mi | |
| 5. | Take exit 15 for I-76 Toll road | 0.4 mi | |
| 6. | Keep right at the fork to continue toward I-76 E and merge onto I-76 E Partial toll road | 18.5 mi | |
| 7. | Take the exit toward PA-66 N Toll road | 0.6 mi | |
| 8. | Keep left at the fork, follow signs for US-119/ Partial toll road | 1.0 mi | |
| 9. | Continue onto PA-66 N/ | 5.6 mi | |
| 10. | Turn right at Coulter St | 423 ft | |
| 11. | Turn left at S Urania Ave | 0.3 mi |
Greensburg, PA |
| 12. | Head northeast on S Urania Ave toward E Pittsburgh St | 0.1 mi | |
| 13. | Turn right at E Pittsburgh St | 1.0 mi | |
| 14. | Take the ramp onto Lincoln Hwy/ Continue to follow Lincoln Hwy/ | 8.2 mi | |
| 15. | Take the ramp onto PA-982 N | 1.3 mi | |
| 16. | Turn left at Lincoln Ave | 1.4 mi | |
| 17. | Turn right at Lincoln Ave/ Continue to follow PA-981 N | 197 ft |
Latrobe, PA |
| 18. | Head southwest on Latrobe Derry Rd/ Continue to follow PA-981 S | 2.8 mi | |
| 19. | Turn right at Lincoln Hwy/ | 6.8 mi | |
| 20. | Slight right at E Pittsburgh St | 1.1 mi | |
| 21. | Turn left at S Urania Ave | 0.1 mi |
Greensburg, PA |
| 22. | Head northeast on S Urania Ave toward E Pittsburgh St | 0.1 mi | |
| 23. | Turn left at E Pittsburgh St | 423 ft | |
| 24. | Continue onto E Otterman St | 0.1 mi | |
| 25. | Turn right at Arch Ave | 0.2 mi | |
| 26. | Take the 1st right onto Beacon St/ Continue to follow US-119 N | 8.7 mi | |
| 27. | Turn right at US-119 N/ Continue to follow US-22 E/ | 23.8 mi | |
| 28. | Take the PA-403 exit toward Dilltown/ | 0.2 mi | |
| 29. | Turn right at Cramer Pike/ Continue to follow PA-403 S | 9.1 mi | |
| 30. | Continue onto Iron St | 0.9 mi | |
| 31. | Turn right at 4th Ave | 0.1 mi | |
| 32. | Take the 1st left onto Power St | 364 ft | |
| 33. | Continue onto Roosevelt Blvd | 0.7 mi | |
| 34. | Continue onto PA-403 S/ | 0.2 mi | |
| 35. | Turn left at Main St | 151 ft | |
| 36. | Take the 1st right to stay on Main St | 0.2 mi | |
| 37. | Take the 3rd right onto Walnut St | 39 ft |
Johnstown, PA |
| 38. | Head northeast on Walnut St toward Main St | 0.2 mi | |
| 39. | Turn right at William Penn Ave | 10.3 mi | |
| 40. | Slight right to merge onto Admiral Peary Hwy/ Continue to follow US-22 E | 24.1 mi | |
| 41. | Exit onto US-22 E toward PA-764 N/ | 0.8 mi | |
| 42. | Exit onto PA-764 N toward Altoona | 4.7 mi | |
| 43. | Turn left at Union Ave | 0.3 mi | |
| 44. | Slight right at 9th Ave | 1.2 mi |
Altoona, PA |
| 45. | Head southwest on 9th Ave toward 7th St | 423 ft | |
| 46. | Take the 2nd right onto 8th St | 433 ft | |
| 47. | Turn left at 10th Ave | 0.8 mi | |
| 48. | Slight right onto the ramp to 18th St | 479 ft | |
| 49. | Turn right at 18th St | 197 ft | |
| 50. | Continue onto Union Ave | 0.7 mi | |
| 51. | Slight right at 7th Ave | 0.5 mi | |
| 52. | Slight right at W 6th Ave/ Continue to follow PA-764 S | 3.7 mi | |
| 53. | Take the ramp onto US-22 W | 0.6 mi | |
| 54. | Merge onto US-22 W via the ramp to Ebensburg | 19.8 mi | |
| 55. | Merge onto US-219 S via the ramp to Johnstown | 14.4 mi | |
| 56. | Take the PA-56 W/ | 0.1 mi | |
| 57. | Merge onto Johnstown Expy Bypass/ Continue to follow PA-56 W | 5.6 mi | |
| 58. | Turn right at Main St | 151 ft | |
| 59. | Take the 1st right to stay on Main St | 0.2 mi | |
| 60. | Take the 3rd right onto Walnut St | 39 ft |
Johnstown, PA |
| 61. | Head northeast on Walnut St toward Main St | 0.2 mi | |
| 62. | Turn right at William Penn Ave | 10.3 mi | |
| 63. | Slight right to merge onto Admiral Peary Hwy/ Continue to follow US-22 E | 24.1 mi | |
| 64. | Take the exit toward I-99 N | 0.8 mi | |
| 65. | Keep left at the fork to continue toward I-99 N and merge onto I-99 N | 41.7 mi | |
| 66. | Exit onto N Atherton St/ | 3.6 mi | |
| 67. | Turn left at W Park Ave | 0.8 mi | |
| 68. | Turn right at Bigler Rd | 0.5 mi |
University Park, PA |
| 69. | Head east on Bigler Rd toward Mc Kean Rd | 236 ft | |
| 70. | Turn left at Hastings Rd | 0.7 mi | |
| 71. | Turn right at the 1st cross street onto Porter Rd | 0.3 mi | |
| 72. | Turn left at E College Ave/ | 0.8 mi | |
| 73. | Take the ramp onto US-322 E | 82.6 mi | |
| 74. | Continue onto US-22 E | 1.8 mi | |
| 75. | Turn right at Maclay St | 0.4 mi | |
| 76. | Turn left at N 7th St | 0.5 mi |
Harrisburg, PA |
| 77. | Head southeast on N 7th St toward Basin St | 0.7 mi | |
| 78. | N 7th St turns slightly right and becomes Walnut St | 0.4 mi | |
| 79. | Turn left at N Front St | 0.5 mi | |
| 80. | Continue onto Randall Shoghart St | 308 ft | |
| 81. | Take the I-83 N ramp to Airport/ | 0.3 mi | |
| 82. | Continue toward I-83 N and merge onto I-83 N | 3.2 mi | |
| 83. | Take exit 46A to merge onto I-283 S toward I-76/ Partial toll road | 3.0 mi | |
| 84. | Take exit 1A to merge onto PA-283 E toward Airport/ Partial toll road | 27.7 mi | |
| 85. | Take the PA-72/ | 0.2 mi | |
| 86. | Keep right at the fork, follow signs for Downtown/ | 2.0 mi | |
| 87. | Turn right at Fruitville Pike/ Continue to follow PA-72 S/ | 1.3 mi | |
| 88. | Turn left at W King St | 0.1 mi |
Lancaster, PA |