Philadelphia, PA to Winston-Salem, NC

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200 km

100 mi

Driving directions to Winston-Salem, NC

551 mi – about 8 hours 57 mins

Philadelphia, PA

1.	Head east on S Penn Square/State Route 611 toward S Broad St Continue to follow S Penn Square	344 ft
2.	Turn left at E Penn Square	0.1 mi
3.	Turn left at John F Kennedy Blvd	1.0 mi
4.	Turn right to stay on John F Kennedy Blvd	295 ft
5.	Take the ramp onto I-76 W	16.9 mi
6.	Take exit 327-328A-328B for US-202 W toward US-422 W/King of Prussia/W Chester/Pottstown	331 ft
7.	Take exit 328A on the left to merge onto US-202 S toward W Chester	11.5 mi
8.	Take the exit onto US-30 W toward Downingtown/Coatesville	36.1 mi
9.	Continue onto Lincoln Hwy E	2.0 mi
10.	Continue onto E King St/PA-462 W	0.7 mi
11.	Turn right at N Broad St	16 ft

68.4 mi – about 1 hour 25 mins

E King St/PA-462

12.	Head north on N Broad St toward Clark St	0.2 mi
13.	Turn right at E Chestnut St/PA-23 E Continue to follow PA-23 E	1.5 mi
14.	Turn left to merge onto US-30 W	3.1 mi
15.	Slight left at PA-283 W (signs for PA-283 W/Harrisburg)	28.5 mi
16.	Take the exit onto I-283 N toward I-81/I-83/Harrisburg	2.6 mi
17.	Take exit 3A on the left to merge onto I-83 S toward Harrisburg Destination will be on the left	2.4 mi

38.3 mi – about 39 mins

I-83 S

18.	Head west on I-83 S toward Exit 44B	2.6 mi
19.	Continue onto PA-581 W	7.2 mi
20.	Take exit 1B on the left to merge onto I-81 S toward Carlisle Passing through Maryland, West Virginia Entering Virginia	278 mi
21.	Slight left at US-220 S (signs for I-581 S/US-220 S/Airport/Roanoke)	0.4 mi
22.	Continue onto I-581 S Destination will be on the right	5.4 mi

293 mi – about 4 hours 30 mins

I-581 S

23.	Head south on I-581 S	236 ft
24.	Take exit 5 for US-11 S toward U.S. 220 Bus S/Downtown	0.2 mi
25.	Slight right at US-11 S/Williamson Rd NE	0.3 mi
26.	Make a U-turn at Campbell Ave SE	0.4 mi
27.	Take the I-581 N/US-220 ramp to Lexington/Salem	0.2 mi
28.	Turn right at I-581 N/US-220 N	5.6 mi
29.	Take exit 1S on the left to merge onto I-81 S toward Salem/Bristol	62.3 mi
30.	Take exit 81 to merge onto I-77 S toward Charlotte NC Entering North Carolina	37.5 mi
31.	Continue onto I-74 E	12.4 mi
32.	Continue onto S Andy Griffith Pkwy	0.3 mi
33.	Continue onto US-52 S	30.6 mi
34.	Take exit 109B to merge onto N Carolina 150 W/I-40 BUS W/US-158 W/US-421 N toward Downtown	0.4 mi
35.	Take exit 5D for Main St toward Downtown/1st St	0.2 mi
36.	Turn right at S Main St	0.4 mi

151 mi – about 2 hours 22 mins

Winston-Salem, NC

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These directions are for planning purposes only. You may find that construction projects, traffic, weather, or other events may cause conditions to differ from the map results, and you should plan your route accordingly. You must obey all signs or notices regarding your route.

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