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200 km
100 mi
Dover, TN |
| 1. | Head west on Spring St toward Main St | 358 ft | |
| 2. | Turn right at Main St/ Continue to follow TN-76 E/ | 7.4 mi | |
| 3. | Turn left at Big Rock Rd | 2.1 mi | |
| 4. | Continue onto Walter Smith Rd | 0.9 mi | |
| 5. | Turn left at Jordan Springs Rd | 2.3 mi | |
| 6. | Turn right at Artillery Rd Entering Kentucky | 4.1 mi | |
| 7. | Continue onto KY-107 E/ Continue to follow KY-107 E | 15.4 mi | |
| 8. | Turn right at Eagle Way/ | 1.3 mi | |
| 9. | Turn left at KY-9004 N | 28.3 mi | |
| 10. | Take exit 34A toward Elizabethtown | 0.4 mi | |
| 11. | Merge onto Wendell H. Ford Western Kentucky Pkwy | 98.2 mi | |
| 12. | Take exit 137B to merge onto I-65 N toward Lexington/ | 39.0 mi | |
| 13. | Take exit 131A to merge onto I-264 E | 11.3 mi | |
| 14. | Take exit 23A to merge onto I-71 N toward Cincinnati | 89.3 mi | |
| 15. | Take exit 191 for 12th St toward Pike St/ | 0.4 mi | |
| 16. | Turn right at W Pike St | 0.6 mi | |
| 17. | Continue onto W 7th St | 0.2 mi |
Covington, KY |
| 18. | Head east on E 7th St toward Scott Blvd | 16 ft | |
| 19. | Take the 1st right onto Scott Blvd | 446 ft | |
| 20. | Take the 1st right onto E 8th St | 0.3 mi | |
| 21. | Turn left at W Pike St | 1.2 mi | |
| 22. | Continue onto Dixie Hwy/ | 2.0 mi | |
| 23. | Turn right to merge onto I-71 S/ Continue to follow I-71 S | 86.5 mi | |
| 24. | Take exit 5 on the left for I-264/ | 0.4 mi | |
| 25. | Merge onto I-264 W | 10.0 mi | |
| 26. | Take exit 12 to merge onto I-65 S toward Nashville Entering Tennessee | 169 mi | |
| 27. | Slight left at I-40 W (signs for I-40 W/ | 99.7 mi | |
| 28. | Take exit 108 for TN-22 toward Huntingdon/ | 0.2 mi | |
| 29. | Turn left at TN-22 S | 11.9 mi | |
| 30. | Turn right at Cook St | 0.6 mi | |
| 31. | Take the 2nd left onto Cook St/ Continue to follow TN-22 Alt S | 8.8 mi | |
| 32. | Turn left to stay on TN-22 Alt S | 4.3 mi | |
| 33. | Turn right at TN-100 W | 5.3 mi | |
| 34. | Turn right at E Main St | 1.8 mi | |
| 35. | Turn left to stay on E Main St | 0.2 mi | |
| 36. | Take the 3rd right onto N Washington Ave | 95 ft |
Henderson, TN |
| 37. | Head southeast on N Washington Ave toward E Main St | 95 ft | |
| 38. | Take the 1st left onto E Main St | 0.2 mi | |
| 39. | Take the 3rd right to stay on E Main St | 1.8 mi | |
| 40. | Turn left at E Main St/ Continue to follow TN-100 E | 21.0 mi | |
| 41. | Turn right at TN-114 S/ Continue to follow TN-114 S | 9.4 mi | |
| 42. | Turn right to stay on TN-114 S | 0.5 mi | |
| 43. | Turn right to stay on TN-114 S | 1.2 mi | |
| 44. | Turn left at TN-114 S/ | 0.8 mi | |
| 45. | Turn right at TN-114 S | 2.3 mi | |
| 46. | Turn right to stay on TN-114 S | 8.2 mi | |
| 47. | Turn right to stay on TN-114 S | 5.5 mi | |
| 48. | Turn left at Savannah Hwy/ | 9.8 mi | |
| 49. | Continue onto US-64 Bypass E | 2.6 mi | |
| 50. | Turn left at Dexter L Woods Memorial Blvd/ Continue to follow TN-15 E/ | 48.1 mi | |
| 51. | Turn left at Fayetteville Hwy/ Continue to follow TN-15 E/ | 0.5 mi | |
| 52. | Turn left at Fayetteville Hwy/ Continue to follow TN-15 E/ | 25.2 mi | |
| 53. | Turn right at Morgan Ave N | 0.2 mi | |
| 54. | Turn left at College St W | 0.7 mi | |
| 55. | Turn left at Mulberry Ave/ Continue to follow TN-15 E/ | 9.5 mi | |
| 56. | Turn left at Smithland Rd | 3.3 mi |
Smithland, TN |
| 57. | Head west on Smithland Rd toward Kelso-Smithland Rd | 3.3 mi | |
| 58. | Turn right at TN-15 W/ Continue to follow TN-15 W/ | 9.5 mi | |
| 59. | Turn right at College St E | 0.7 mi | |
| 60. | Turn right at Morgan Ave N | 0.2 mi | |
| 61. | Turn left at TN-15 W/ Continue to follow TN-15 W/ | 18.2 mi | |
| 62. | Turn right to merge onto I-65 N | 23.2 mi | |
| 63. | Take exit 37 for TN-50 toward Lewisburg/ | 0.1 mi | |
| 64. | Turn left at New Lewisburg Hwy/ Continue to follow TN-50 W | 13.6 mi | |
| 65. | Turn left at Hampshire Pike | 1.1 mi | |
| 66. | Slight right at TN-50 W/ | 9.8 mi | |
| 67. | Turn left to stay on TN-50 W/ Continue to follow TN-50 W | 3.9 mi | |
| 68. | Turn right to stay on TN-50 W | 13.1 mi | |
| 69. | Turn left to stay on TN-50 W | 17.7 mi | |
| 70. | Turn left to merge onto I-40 W | 137 mi | |
| 71. | Take exit 108 to merge onto I-40 W toward Little Rock | 13.0 mi | |
| 72. | Take exit 1C for US-51/ | 0.2 mi | |
| 73. | Merge onto N Danny Thomas Blvd/ | 0.3 mi | |
| 74. | Turn right at Poplar Ave | 0.3 mi |
Memphis, TN |
| 75. | Head east on Poplar Ave toward N 3rd St | 0.3 mi | |
| 76. | Turn left at N Danny Thomas Blvd | 0.2 mi | |
| 77. | Take the 2nd right onto Alabama Ave | 384 ft | |
| 78. | Turn left to merge onto I-40 E toward Nashville | 0.9 mi | |
| 79. | Take exit 1E to merge onto I-240 S toward Jackson Miss | 5.6 mi | |
| 80. | Take the exit onto I-55 S Entering Mississippi | 193 mi | |
| 81. | Take exit 104 to merge onto I-220 S toward Jackson W | 11.4 mi | |
| 82. | Take the exit onto I-20 W toward Vicksburg | 36.7 mi | |
| 83. | Take exit 4B toward W Clay St/ | 0.4 mi | |
| 84. | Merge onto Clay St/ Continue to follow Clay St | 1.9 mi | |
| 85. | Turn right at Adams St | 0.2 mi | |
| 86. | Take the 3rd left onto Jackson St | 279 ft |
Vicksburg, MS |
| 87. | Head west on Jackson St toward Cherry St | 0.2 mi | |
| 88. | Turn left at S Washington St | 3.3 mi | |
| 89. | Continue onto Warrenton Rd | 2.6 mi | |
| 90. | Continue onto US-61 S | 63.7 mi | |
| 91. | Continue onto Devereaux Dr | 1.0 mi | |
| 92. | Continue onto St Catherine St | 0.8 mi | |
| 93. | Continue onto Jefferson St/ | 0.2 mi | |
| 94. | Turn left at N Commerce St | 0.1 mi | |
| 95. | Turn right at Main St | 351 ft | |
| 96. | Take the 1st right onto N Pearl St | 89 ft |
Natchez, MS |