Cincinnati, Hamilton, Ohio |
| 1. | Head northeast on Victory Pkwy toward Ledgewood Dr | 1.0 mi | |
| 2. | Slight left at Sherman Ave | 128 ft | |
| 3. | Turn right at Reading Rd | 0.7 mi | |
| 4. | Turn left to merge onto OH-562 W toward I-75 | 0.9 mi | |
| 5. | Take the exit onto I-75 N toward Dayton | 45.5 mi | |
| 6. | Take exit 53A for 3rd St | 0.2 mi | |
| 7. | Turn right at W 3rd St | 0.5 mi | |
| 8. | Turn right at S Main St | 223 ft |
Dayton, OH |
| 9. | Head north on S Main St toward W 3rd St | 0.8 mi | |
| 10. | Turn right at E Grand Ave | 289 ft | |
| 11. | Merge onto I-75 N via the ramp on the left to OH-4/ | 6.4 mi | |
| 12. | Take exit 61 to merge onto I-70 E toward Columbus | 62.2 mi | |
| 13. | Slight left at I-670 E (signs for I-670 E/ | 4.9 mi | |
| 14. | Take exit 5B on the left to merge onto I-71 N toward Cleveland | 139 mi | |
| 15. | Merge onto I-90 E | 1.3 mi | |
| 16. | Take exit 171B for OH-14 W/ | 0.2 mi | |
| 17. | Merge onto S Broadway Ave/ | 0.2 mi | |
| 18. | Continue straight onto Ontario St | 0.5 mi | |
| 19. | Turn left at W Superior Ave | 0.1 mi | |
| 20. | Turn right at W 3rd St | 213 ft | |
| 21. | Take the 1st right onto Blackstone Ct | 157 ft |
Cleveland, OH |
| 22. | Head southwest on Blackstone Ct toward W 3rd St | 157 ft | |
| 23. | Turn left at W 3rd St | 213 ft | |
| 24. | Turn left at W Superior Ave | 0.1 mi | |
| 25. | Take the 1st right onto Ontario St | 0.6 mi | |
| 26. | Take the ramp onto I-90 W Partial toll road | 99.7 mi | |
| 27. | Take exit 71 to merge onto I-280 N toward Toledo/ Partial toll road | 13.0 mi | |
| 28. | Take the exit onto I-75 N toward I-475/ Entering Michigan | 52.9 mi | |
| 29. | Take the exit toward Rosemont Ave | 0.6 mi | |
| 30. | Continue toward MI-10 S | 0.4 mi | |
| 31. | Keep right at the fork, follow signs for MI-10 S/ | 1.3 mi | |
| 32. | Turn left at Woodward Ave | 0.2 mi | |
| 33. | Turn right at Cadillac Square | 121 ft |
Detroit, MI |
| 34. | Head east on Cadillac Square toward Bates St | 0.1 mi | |
| 35. | Take the 2nd right onto Randolph St | 0.2 mi | |
| 36. | Turn left at E Jefferson Ave | 0.2 mi | |
| 37. | Continue onto I-375 N | 1.3 mi | |
| 38. | Continue onto I-75 N | 59.4 mi | |
| 39. | Slight right at I-475 N | 6.5 mi | |
| 40. | Take exit 7 to merge onto MI-21 W toward Downtown/ | 0.3 mi | |
| 41. | Turn left at E Court St | 0.3 mi |
Flint, MI |
| 42. | Head southwest on E Court St toward S Saginaw St | 0.2 mi | |
| 43. | Turn left at S Grand Traverse St | 0.3 mi | |
| 44. | Turn right to merge onto I-69 W | 55.0 mi | |
| 45. | Take exit 81 to merge onto I-96 W toward Grand Rapids | 53.6 mi | |
| 46. | Slight left at I-196 W (signs for I-196/ | 3.5 mi | |
| 47. | Take exit 77C for Ottawa Ave toward Downtown | 0.3 mi | |
| 48. | Merge onto Ottawa Ave NW | 220 ft | |
| 49. | Turn left at Michigan St NW | 0.1 mi | |
| 50. | Turn right at Division Ave NE/ Continue to follow Division Ave NE | 0.5 mi |
Grand Rapids, MI |
| 51. | Head north on Division Ave N toward Monroe Center St NE | 0.4 mi | |
| 52. | Slight right at Division Ave NE/ | 0.1 mi | |
| 53. | Turn left at Michigan St NE | 236 ft | |
| 54. | Take the 1st right onto Ionia Ave NW | 0.1 mi | |
| 55. | Slight left to merge onto I-196 W toward Holland | 76.9 mi | |
| 56. | Continue onto US-31 S (signs for US-31 S/ | 0.5 mi | |
| 57. | Merge onto I-94 W Entering Indiana | 63.7 mi | |
| 58. | Take exit 16 for IN-51/ Partial toll road | 0.6 mi | |
| 59. | Follow signs for I-90 W/ Partial toll road Entering Illinois | 34.1 mi | |
| 60. | Take exit 53A toward Canallport Ave/ | 0.3 mi | |
| 61. | Slight left at S Ruble St | 285 ft | |
| 62. | Slight left toward S Canalport Ave | 102 ft | |
| 63. | Turn left at S Canalport Ave | 0.4 mi | |
| 64. | Slight right at W Cermak Rd | 59 ft | |
| 65. | Take the 1st left onto S Morgan St | 0.1 mi |
Chicago, IL |
| 66. | Head north on S Morgan St toward W Cermak Rd | 0.1 mi | |
| 67. | Turn right at W Cermak Rd | 59 ft | |
| 68. | Slight left at S Canalport Ave | 0.3 mi | |
| 69. | Turn right onto the ramp to I-90 E/ | 0.1 mi | |
| 70. | Keep left at the fork, follow signs for I-90 E/ Continue to follow I-94 E | 9.8 mi | |
| 71. | Slight right at I-57 S | 13.4 mi | |
| 72. | Take exit 345B to merge onto I-80 W toward Iowa | 19.6 mi | |
| 73. | Take exit 131 for Center St | 0.3 mi | |
| 74. | Turn right at Raynor Ave | 0.1 mi | |
| 75. | Continue onto Center St | 0.5 mi | |
| 76. | Slight right to stay on Center St | 262 ft | |
| 77. | Continue onto S Hickory St | 0.2 mi | |
| 78. | Turn right at W Jefferson St | 0.4 mi |
Joliet, IL |
| 79. | Head east on W Jefferson St toward N Chicago St | 443 ft | |
| 80. | Take the 2nd left onto N Scott St | 0.2 mi | |
| 81. | Take the 3rd left onto E Cass St | 0.3 mi | |
| 82. | Continue onto Western Ave | 0.3 mi | |
| 83. | Turn right at N Center St | 0.3 mi | |
| 84. | N Center St turns slightly left and becomes Plainfield Rd/ | 5.2 mi | |
| 85. | Turn right to merge onto I-55 N toward Chicago | 19.3 mi | |
| 86. | Take exit 277A to merge onto I-294 N toward Wisconsin Partial toll road | 30.4 mi | |
| 87. | Merge onto I-94 W Partial toll road Entering Wisconsin | 63.3 mi | |
| 88. | Continue onto I-43 N | 119 mi | |
| 89. | Take exit 192A to merge onto US-141 N/ | 15.8 mi | |
| 90. | Continue straight onto US-141 N | 5.4 mi | |
| 91. | Turn left at Co Rd I | 4.1 mi | |
| 92. | Turn left at S Main St | 2.1 mi | |
| 93. | Continue onto WI-22 S | 7.6 mi | |
| 94. | Turn right at WI-32 N | 57.7 mi | |
| 95. | Turn right at Pine St/ | 374 ft | |
| 96. | Turn left at US-8 E | 0.4 mi | |
| 97. | Continue onto Linden St | 75 ft |
Laona, WI |
| 98. | Head south on Linden St toward US-8 E | 75 ft | |
| 99. | Continue straight onto US-8 W | 0.4 mi | |
| 100. | Turn right at Pine St/ Continue to follow US-8 W | 11.4 mi | |
| 101. | Continue onto W Pioneer St/ Continue to follow WI-55 S | 4.0 mi | |
| 102. | Turn right at Co Hwy B/ Continue to follow Co Hwy B | 6.0 mi | |
| 103. | Slight left toward Co Hwy B | 0.2 mi | |
| 104. | Continue straight onto Co Hwy B | 0.2 mi | |
| 105. | Turn right to stay on Co Hwy B | 4.8 mi | |
| 106. | Turn left at US-45 S/ | 8.3 mi | |
| 107. | Turn right at Co Rd T | 2.7 mi | |
| 108. | Continue onto T | 4.8 mi | |
| 109. | Turn right to stay on T | 1.5 mi | |
| 110. | Turn left at H | 2.0 mi | |
| 111. | Turn right at CC | 3.0 mi | |
| 112. | Continue onto Co Rd CCC | 2.0 mi | |
| 113. | Turn left at WI-17 S | 15.0 mi | |
| 114. | Turn right at WI-64 W | 0.3 mi | |
| 115. | Turn left to merge onto US-51 S | 20.4 mi | |
| 116. | Continue onto I-39 S | 63.4 mi | |
| 117. | Take exit 124 for WI-21 toward Necedah/ | 0.2 mi | |
| 118. | Turn right at WI-21 W | 29.1 mi | |
| 119. | Turn left at S Main St/ Continue to follow WI-80 S | 4.0 mi | |
| 120. | Turn right to stay on WI-80 S | 7.1 mi | |
| 121. | Turn right to merge onto I-90 W/ Continue to follow I-90 W Entering Minnesota | 177 mi | |
| 122. | Take exit 159A to merge onto I-35 S toward Albert Lea/ Entering Iowa | 145 mi | |
| 123. | Take the exit onto I-35 S/ Continue to follow I-35 S Entering Missouri | 168 mi | |
| 124. | Take exit 33 for Missouri PP toward Lawson/ | 0.2 mi | |
| 125. | Turn left at Missouri PP | 4.3 mi | |
| 126. | Turn right at US-69 S | 6.9 mi | |
| 127. | Turn left at NE 152nd St | 0.7 mi | |
| 128. | Turn right at Salem Rd | 1.3 mi | |
| 129. | Turn right at Kennedy Ave | 0.2 mi | |
| 130. | Take the 1st right onto McIver St | 108 ft | |
| 131. | McIver St turns left and becomes Caldwell St | 0.2 mi | |
| 132. | Continue onto N Marietta St | 0.3 mi | |
| 133. | Turn right at South St | 243 ft | |
| 134. | Take the 1st left onto S Thompson Ave | 0.2 mi |
Excelsior Springs, MO |
| 135. | Head west on S Thompson Ave toward St Louis Ave | 75 ft | |
| 136. | Take the 1st left onto St Louis Ave | 157 ft | |
| 137. | Take the 1st left to stay on St Louis Ave | 0.1 mi | |
| 138. | Continue onto Isley Blvd/ Continue to follow MO-10 E | 13.8 mi | |
| 139. | Turn left to stay on MO-10 E | 2.6 mi | |
| 140. | Take the MO-13 ramp to Polo | 0.4 mi | |
| 141. | Turn right at MO-13 S/ Continue to follow MO-13 S | 9.2 mi | |
| 142. | Take the MO-13 S ramp | 0.2 mi | |
| 143. | Turn left at MO-13 S/ | 2.2 mi | |
| 144. | Take the MO-13 ramp to Lexington | 0.2 mi | |
| 145. | Turn right at MO-13 S | 1.0 mi | |
| 146. | Continue onto State Hwy O | 1.0 mi | |
| 147. | Turn left to stay on State Hwy O | 9.3 mi | |
| 148. | Turn left to merge onto I-70 E/ Continue to follow I-70 E | 206 mi | |
| 149. | Take exit 247 toward Grand Blvd | 0.1 mi | |
| 150. | Turn right at E Grand Ave | 0.2 mi | |
| 151. | At the traffic circle, take the 2nd exit and stay on E Grand Ave | 1.9 mi | |
| 152. | Turn left at Cozens Ave | 446 ft |
Saint Louis, MO |
| 153. | Head southeast on Cozens Ave toward Francis St | 115 ft | |
| 154. | Take the 1st right onto Francis St | 0.1 mi | |
| 155. | Turn left at Dr Martin Luther King Dr | 0.9 mi | |
| 156. | Turn right at N Jefferson Ave | 0.5 mi | |
| 157. | Turn left at Market St | 0.5 mi | |
| 158. | Turn right at S 18th St | 0.7 mi | |
| 159. | Continue onto Truman Pkwy | 0.5 mi | |
| 160. | Take the ramp onto I-55 S | 78.2 mi | |
| 161. | Take exit 129 for MO-51/ | 0.3 mi | |
| 162. | Turn right at MO-51 S/ Continue to follow MO-51 S | 34.1 mi | |
| 163. | Turn right at Conrad Ave | 0.3 mi | |
| 164. | Continue onto W Main St | 0.2 mi | |
| 165. | Turn left at 1st St | 0.2 mi | |
| 166. | Turn right at Lutes St/ Continue to follow MO-51 S | 2.0 mi | |
| 167. | Turn right at Missouri FF | 7.0 mi | |
| 168. | Turn left at Missouri H | 5.5 mi | |
| 169. | Turn right at MO-51 S | 16.6 mi | |
| 170. | Turn left at E Richardson Ave | 351 ft |
Puxico, MO |
| 171. | Head southeast on E Richardson Ave/ Continue to follow State Hwy Pp | 9.9 mi | |
| 172. | Turn right at State Hwy M | 5.7 mi | |
| 173. | Turn right at MO-25 S | 1.0 mi | |
| 174. | Turn left at State Hwy Ab | 14.4 mi | |
| 175. | Continue onto State Hwy Y | 3.1 mi | |
| 176. | Turn right at State Hwy Bb | 2.0 mi | |
| 177. | Continue onto State Hwy Ff | 1.2 mi | |
| 178. | Turn left at US-60 E | 5.8 mi | |
| 179. | Continue onto I-57 N Entering Illinois | 51.9 mi | |
| 180. | Take the exit toward 770N/ | 0.2 mi | |
| 181. | Turn right at 770N/ Continue to follow IL-146 E | 37.5 mi | |
| 182. | Continue onto Main St | 0.1 mi |
Golconda, IL |
| 183. | Head west on Main St toward Franklin St | 0.1 mi | |
| 184. | Take the 2nd right onto Adams St/ Continue to follow IL-146 E | 9.5 mi | |
| 185. | Turn left at IL-34 N | 7.4 mi | |
| 186. | Turn right at 1180 N/ Continue to follow Karbers Ridge Rd | 8.3 mi | |
| 187. | Continue onto Pounds Hollow Rd | 1.4 mi | |
| 188. | Continue onto 5600E/ | 1.7 mi | |
| 189. | Turn left at 2750N/ | 8.7 mi | |
| 190. | Turn right at IL-13 E Entering Kentucky | 9.1 mi | |
| 191. | Continue onto KY-56 E | 12.8 mi |
Morganfield, KY |
| 192. | Head southeast on KY-56 E/ Continue to follow KY-56 E | 7.3 mi | |
| 193. | Turn right at State Hwy 983 | 11.7 mi | |
| 194. | Turn right to stay on State Hwy 983 | 0.1 mi | |
| 195. | Turn right at Main St | 0.3 mi | |
| 196. | Take the 3rd left onto KY-132 N/ Continue to follow KY-132 N | 0.7 mi | |
| 197. | Turn right at State Hwy 630 | 12.8 mi | |
| 198. | Turn left at Nebo Rd/ | 5.2 mi | |
| 199. | Continue onto Island Ford Rd/ | 0.6 mi | |
| 200. | Slight right onto the Pennyrile Pkwy S ramp to Hopkinville | 0.2 mi | |
| 201. | Merge onto KY-9004 S | 10.0 mi | |
| 202. | Take exit 34A toward Elizabethtown | 0.3 mi | |
| 203. | Merge onto Wendell H. Ford Western Kentucky Pkwy | 13.9 mi | |
| 204. | Take exit 53 for KY-181 toward Sacramento/ | 0.5 mi | |
| 205. | Turn right at KY-181 S | 2.3 mi | |
| 206. | Turn left at W Depot St/ Continue to follow W Depot St | 0.9 mi | |
| 207. | Turn right at Main St | 0.8 mi | |
| 208. | Turn right at W Main Cross St | 102 ft |
Greenville, KY |
| 209. | Head east on W Main Cross St toward Main St | 102 ft | |
| 210. | Take the 1st left onto Main St | 0.8 mi | |
| 211. | Turn left at W Depot St | 0.9 mi | |
| 212. | Turn right at KY-181 N | 2.3 mi | |
| 213. | Turn left to merge onto Wendell H. Ford Western Kentucky Pkwy | 24.3 mi | |
| 214. | Take exit 77A for William H Natcher Pkwy S toward Bowling Green | 0.4 mi | |
| 215. | Merge onto KY-9007 S | 40.8 mi | |
| 216. | Take exit 1B to merge onto I-65 N toward Louisville | 27.0 mi | |
| 217. | Take exit 48 for KY-255 toward Park City/ | 0.3 mi | |
| 218. | Turn left at KY-255/ | 2.4 mi | |
| 219. | Continue straight onto KY-70 W | 2.5 mi | |
| 220. | Slight right at Mammoth Cave Entrance Rd | 3.0 mi | |
| 221. | Turn left to stay on Mammoth Cave Entrance Rd | 305 ft |
Mammoth Cave, KY |
| 222. | Head northeast toward Mammoth Cave Entrance Rd | 266 ft | |
| 223. | Continue straight onto Mammoth Cave Entrance Rd | 39 ft | |
| 224. | Turn right to stay on Mammoth Cave Entrance Rd | 1.3 mi | |
| 225. | Turn left at Violet City Rd | 2.2 mi | |
| 226. | Continue onto KY-255/ | 2.0 mi | |
| 227. | Continue straight onto KY-70 E/ Continue to follow KY-70 E | 3.6 mi | |
| 228. | Turn left to merge onto I-65 N | 72.6 mi | |
| 229. | Take exit 125A to merge onto Gene Snyder Fwy/ | 16.4 mi | |
| 230. | Take exit 27 for US-60/ | 0.2 mi | |
| 231. | Turn right at Shelbyville Rd/ | 8.3 mi | |
| 232. | Turn left at 3rd St/ | 66 ft |
Simpsonville, KY |
| 233. | Head south on 3rd St/ | 66 ft | |
| 234. | Turn left at Midland Trail/ | 0.6 mi | |
| 235. | Turn right at Buckcreek Rd/ | 0.4 mi | |
| 236. | Continue onto Simpsonville-Buck Creek Rd | 0.7 mi | |
| 237. | Turn left to merge onto I-64 E | 93.3 mi | |
| 238. | Take exit 121 for KY-36 toward Frenchburg/ | 0.3 mi | |
| 239. | Turn right at KY-36 E | 16.7 mi | |
| 240. | Turn right at Walnut St | 79 ft |
Frenchburg, KY |
| 241. | Head east on Walnut St toward US-460 E | 79 ft | |
| 242. | Take the 1st left onto KY-36 W | 16.8 mi | |
| 243. | Turn left to merge onto I-64 W toward Lexington | 25.0 mi | |
| 244. | Take exit 96A to merge onto KY-627 S/ Continue to follow KY-627 S | 2.0 mi | |
| 245. | Turn right at Boone Ave | 1.3 mi | |
| 246. | Continue onto Boonesboro Rd/ Continue to follow KY-627 S | 12.4 mi | |
| 247. | Turn left to merge onto I-75 S toward Khoiville | 84.1 mi | |
| 248. | Take exit 11 toward KY-92 W | 0.2 mi | |
| 249. | Turn right at KY-92 W | 20.0 mi | |
| 250. | Continue onto Old U.S. 27 S | 0.3 mi | |
| 251. | Slight left to stay on Old U.S. 27 S | 102 ft | |
| 252. | Turn left to stay on Old U.S. 27 S | 0.6 mi | |
| 253. | Take the 1st right onto M Ross Rd/ | 59 ft |
Pine Knot, KY |
| 254. | Head east on M Ross Rd/ | 59 ft | |
| 255. | Turn right at Old U.S. 27 S | 1.6 mi | |
| 256. | Turn right at KY-1470 W/ Continue to follow US-27 S Entering Tennessee | 11.1 mi | |
| 257. | Turn left at Depot St/ Continue to follow TN-297 E | 7.3 mi | |
| 258. | Turn right at Anna Dell Rd/ Continue to follow TN-297 E | 2.7 mi | |
| 259. | Turn left at Baker Hwy/ Continue to follow TN-63 E/ | 13.9 mi | |
| 260. | Turn right to merge onto I-75 S/ Continue to follow I-75 S | 33.1 mi | |
| 261. | Slight left at I-275 S | 0.4 mi | |
| 262. | Take exit 3 to merge onto I-640 E toward Asheville | 6.9 mi | |
| 263. | Continue onto US-25W S (signs for I-40 E/ | 0.6 mi | |
| 264. | Merge onto I-40 E | 13.9 mi | |
| 265. | Take exit 407 toward Winfield Dunn Pkwy | 0.3 mi | |
| 266. | Turn right at Winfield Dunn Pkwy | 8.5 mi | |
| 267. | Continue onto Forks of the River Pkwy/ | 0.6 mi | |
| 268. | Turn right at Parkway/ Continue to follow TN-71 S/ | 19.7 mi | |
| 269. | Turn left to stay on TN-71 S/ Continue to follow US-441 S Entering North Carolina | 27.5 mi | |
| 270. | Turn right at US-19 S/ | 0.5 mi | |
| 271. | Take the 1st left onto US-441 S | 5.2 mi | |
| 272. | Take the ramp onto Great Smoky Mountains Expy/ | 7.3 mi | |
| 273. | Merge onto US-23 S/ | 16.8 mi | |
| 274. | Exit onto Hunnicutt Ln/ Continue to follow E Main St/ | 1.5 mi | |
| 275. | Turn right at Iotla St/ | 161 ft |
Franklin, NC |
| 276. | Head south on Iotla St/ | 161 ft | |
| 277. | Continue onto Phillips St/ | 358 ft | |
| 278. | Turn left at E Palmer St | 0.3 mi | |
| 279. | Continue onto E Main St | 1.1 mi | |
| 280. | Slight right to merge onto Sylva Rd/ | 0.5 mi | |
| 281. | Make a U-turn at Cat Creek Rd/ Continue to follow US-23 N/ | 17.0 mi | |
| 282. | Merge onto Great Smoky Mountains Expy/ Continue to follow Great Smoky Mountains Expy/ | 25.9 mi | |
| 283. | Merge onto I-40 E | 19.1 mi | |
| 284. | Take exit 47 for N Carolina 191 toward W Asheville/ | 0.1 mi | |
| 285. | Turn right at Brevard Rd/ | 0.7 mi | |
| 286. | Turn right to merge onto I-240 E/ | 2.7 mi | |
| 287. | Take exit 4A on the left to merge onto I-26 W/ Continue to follow I-26 W/ Entering Tennessee | 61.6 mi | |
| 288. | Take exit 20B to merge onto N Roan St/ Continue to follow N Roan St | 0.9 mi | |
| 289. | Slight right at TN-34 N/ Continue to follow TN-34 N/ | 20.8 mi |
Bristol, TN |
| 290. | Head north on TN-34 N/ Continue to follow US-11E N/ Entering Virginia | 0.6 mi | |
| 291. | Continue onto Commonwealth Ave/ | 0.6 mi | |
| 292. | Continue onto I-381 N | 1.1 mi | |
| 293. | Take exit 1A to merge onto I-81 N toward Roanoke | 11.1 mi | |
| 294. | Take exit 14 for VA-140 toward US-19 N/ | 0.2 mi | |
| 295. | Turn right at Co Rd 647/ Continue to follow Old Jonesboro Rd/ | 0.5 mi | |
| 296. | Turn right at W Main St | 0.9 mi | |
| 297. | Turn left at US-19 N | 12.7 mi | |
| 298. | Turn left at State Route 614/ Continue to follow US-58 Alt W | 26.0 mi | |
| 299. | Take the exit toward VA-158 N/ | 0.2 mi | |
| 300. | Turn right at VA-158 N/ | 0.1 mi | |
| 301. | Turn left at Front St E | 0.2 mi | |
| 302. | Take the 2nd right | 157 ft | |
| 303. | Turn left | 0.1 mi |
Coeburn, VA |
| 304. | Head east toward Grand Ave NE | 0.1 mi | |
| 305. | Take the 2nd right toward Front St E | 157 ft | |
| 306. | Turn left at Front St E | 0.2 mi | |
| 307. | Turn right at VA-158 S/ Continue to follow VA-72 S | 0.2 mi | |
| 308. | Turn left to merge onto US-58 Alt E | 26.2 mi | |
| 309. | Turn right at US-19 S/ | 12.2 mi | |
| 310. | Turn left at Russell Rd NW/ | 1.0 mi | |
| 311. | Turn left at W Main St/ | 0.2 mi | |
| 312. | Take the 2nd right onto Cummings St/ | 0.8 mi | |
| 313. | Turn left to merge onto I-81 N/ Continue to follow I-81 N | 26.0 mi | |
| 314. | Take exit 44 for US-11 toward Marion | 0.3 mi | |
| 315. | Turn right at Lee Hwy/ Continue to follow US-11 N | 2.1 mi | |
| 316. | Continue onto E Main St | 308 ft |
Marion, VA |
| 317. | Head southwest on E Main St toward Acton Pl | 0.1 mi | |
| 318. | Take the 3rd left onto S Commerce St | 0.7 mi | |
| 319. | Take the ramp onto I-81 S | 20.6 mi | |
| 320. | Take exit 24 for VA-80 toward Meadowview | 0.1 mi | |
| 321. | Turn right at Co Rd 50/ | 0.3 mi | |
| 322. | Turn left at Co Rd 50/ | 0.2 mi | |
| 323. | Turn right at Co Rd 50/ | 0.4 mi | |
| 324. | Turn left at Co Rd 50/ Continue to follow VA-80 W | 10.2 mi | |
| 325. | Turn right at Hayters Gap Rd/ | 0.2 mi | |
| 326. | Turn left to stay on Hayters Gap Rd/ Continue to follow VA-80 W | 9.0 mi | |
| 327. | Turn right at Trail of the Lonesome Pine/ | 2.6 mi | |
| 328. | Turn left at Honaker Rd/ Continue to follow Red Bud Hwy/ | 5.7 mi | |
| 329. | Turn right at Main St/ Continue to follow VA-80 W | 26.3 mi | |
| 330. | Turn right at Main St/ Continue to follow VA-80 W Entering Kentucky | 11.1 mi | |
| 331. | VA-80 W turns slightly right and becomes KY-80 W | 0.2 mi | |
| 332. | Turn left to stay on KY-80 W | 161 ft | |
| 333. | Turn left to stay on KY-80 W | 3.8 mi | |
| 334. | Turn right at Elkhorn St/ Continue to follow KY-80 W | 3.0 mi | |
| 335. | Turn left at KY-80 W/ Continue to follow KY-80 W/ | 26.4 mi | |
| 336. | Turn right at KY-80 W/ Continue to follow US-23 N/ | 15.2 mi | |
| 337. | Turn right at Cr-3384/ | 1.6 mi | |
| 338. | Slight left to stay on Cr-3384/ | 0.3 mi | |
| 339. | Take the 1st right onto W Graham St | 0.1 mi |
Prestonsburg, KY |
| 340. | Head northeast on W Graham St toward N Lake Dr | 49 ft | |
| 341. | Take the 1st left onto N Lake Dr | 0.9 mi | |
| 342. | Slight left at KY-1428 N | 1.0 mi | |
| 343. | Turn right at Abbott Mountain Rd/ | 1.4 mi | |
| 344. | Turn right at Timberline St/ Continue to follow US-23 N | 59.4 mi | |
| 345. | Slight right to merge onto I-64 E Entering West Virginia | 58.4 mi | |
| 346. | Take exit 58B for US-119 N/ | 0.2 mi | |
| 347. | Slight left at Pennsylvania N | 0.2 mi | |
| 348. | Turn right at Lee St W | 0.8 mi | |
| 349. | Turn right at Dickinson St | 30 ft |
Charleston, WV |



























